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A 45-year-old man with elevated levels of immunoglobulin A

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Quantitative immunoglobulin tests are often ordered as part of the initial evaluation for suspected immune deficiency. Although alterations in immunoglobulin levels can explain recurrent infections, in a patient without symptoms, there are a variety of other factors that can alter immunoglobulin levels. Common causes for elevated immunoglobulin A levels include malignancy and hepatic impairment in addition to a variety of infiltrative, infectious, and inflammatory diseases. We present a case of a 45-year-old man with a history of recurrent sinopulmonary symptoms without bacterial infection found to have an isolated elevated level of immunoglobulin A.
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Keywords: Elevated immunoglobulin A; IgA; antibody; gammopathy; hypergammaglobulin; immunoglobulin; liver disease; rhinitis

Document Type: Research Article

Affiliations: 1: From the Department of Clinical Immunology and Allergy, Southern California Permanente Medical Group, Los Angeles, California 2: Department of Clinical Immunology and Allergy, University of California Los Angeles, Los Angeles, California

Publication date: September 1, 2018

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