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A 47-year-old man with tongue swelling

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Intermittent tongue angioedema can be the initial presentation of several disorders including angiotensin-converting-enzyme inhibitor induced angioedema and hereditary angioedema. Persistent angioedema on the other hand, can be associated with amyloidosis, tumors, thyroid disorders and acromegaly. We present a case of intermittent episodes of tongue swelling progressing to macroglossia.
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Keywords: Acromegaly; amyloidosis; angioedema; growth hormone excess; multiple myeloma; pituitary adenoma; tongue swelling

Document Type: Research Article

Affiliations: Department of Medicine, Rheumatology and Allergy and Immunology Division, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico

Publication date: July 1, 2016

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  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

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    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

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    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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