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New Frontiers in Immunotherapy

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Traditional allergen immunotherapy has been shown to be effective in numerous studies and can affect the natural course of allergic diseases. However, knowledge gained from cytokine regulation and vaccines as immuno-modifiers have shed new insight into other forms of immunotherapy. Novel routes, the role of allergen vaccines, and humanized anti-IgE and DNA-based immunization are the new frontiers of immunotherapy. This review considers both humoral and cellular response, mechanisms, and investigations at our center and the role of anti-IgE-based immunization as other strategies.

Document Type: Research Article

Publication date: 01 September 1999

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  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma and by having the potential to directly impact the quality of patient care. AAP welcomes the submission of original works including peer-reviewed original research and clinical trial results. Additionally, as the official journal of the Eastern Allergy Conference (EAC), AAP will publish content from EAC poster sessions as well as review articles derived from EAC lectures.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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