Molecular Bases for the Construction of Artificial Immunogens and Vaccines Based on Synthetic Polyions
The molecular and cellular mechanisms of action of synthetic polyions on immunogenesis are reviewed. The results of studies of principal properties of polyionic immunostimulators and of the cell responses to the action of these stimulants have been used to construct artificial antigen-polyion complexes with enhanced immunogenic properties. The immunizing properties of such macromolecular complexes, constructed with the use of bacterial or viral antigens, are analyzed.
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Document Type: Research Article
Publication date: 01 September 1995
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- Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.
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