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Effect of Allergy Medication on Children's Reading Comprehension

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The impact of a very common over-the-counter antihistamine, chlorpheniramine, was measured in respect to the reading comprehension of 12 normal school-age children (5 boys and 7 girls) who had a history of allergic rhinitis. Each subject served as his/her own control, and a double-blind design was employed. Each child's parent was given two bottles of cherry syrup and told to administer the syrup in Bottle A for 3 days and then that in Bottle B for 3 days according to directions on the bottle. Parents and children did not know which bottle contained the medication. One of the two forms of a standardized reading comprehension test was administered at the end of each 3-day period in the allergist's office by a trained test administrator. Students were randomly assigned to the two conditions and to the form of the test administered. The mean reading comprehension scores of the drug and placebo drugs were 59 and 60, respectively, which were not significantly different. This study would indicate that common across-the-counter antihistamines should not adversely affect typical school activities such as reading comprehension if used appropriately. Even if some drowsiness or inattention may occur, children's cognitive functions are not affected sufficiently to disrupt learning.
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Document Type: Research Article

Publication date: September 1, 1990

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma and by having the potential to directly impact the quality of patient care. AAP welcomes the submission of original works including peer-reviewed original research and clinical trial results. Additionally, as the official journal of the Eastern Allergy Conference (EAC), AAP will publish content from EAC poster sessions as well as review articles derived from EAC lectures.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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