Immunologic Aspects of Eosinophilia
There is compelling investigative data to indicate that the eosinophil may be more than just coincidentally involved in immune system function. In concert with IgE and the mast cell it is likely that eosinophil actions evolved as an early host defense mechanism against helminth parasites. Thus, a reasonable basis exists for the concept that in the evolutionary scheme there emerged genetically endowed humans with the potential for mounting immediate hypersensitivity responses to multicellular and complex antigenic particulates and animal and plant products, e.g., pollens and danders; hence the atopic state, allergic reactivity and the eosinophil. In many instances there is reason to interpret and ascribe a benign nature to eosinophil accumulations. In other circumstances, associations with hypersensitivity inflammation, for better or for worse, are viewed with especial interest by eosinophil watchers as the unraveling of allergic phenomena continues.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
Document Type: Research Article
Publication date: September 1, 1985
More about this publication?
- Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.
The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma and by having the potential to directly impact the quality of patient care. AAP welcomes the submission of original works including peer-reviewed original research and clinical trial results. Additionally, as the official journal of the Eastern Allergy Conference (EAC), AAP will publish content from EAC poster sessions as well as review articles derived from EAC lectures.
Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.
Articles marked "F" offer free full text for personal noncommercial use only.
The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
- Editorial Board
- Information for Authors
- Submit a Paper
- Information for Advertisers
- Reprint Requests
- Ingenta Connect is not responsible for the content or availability of external websites