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Ferritin heavy/light chain (FTH1/FTL) expression, serum ferritin levels, and their functional as well as prognostic roles in acute myeloid leukemia

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We previously reported the prognostic value of serum ferritin in younger patients with intermediate‐risk acute myeloid leukemia (AML). The aims of this study were to confirm this finding in a larger cohort regardless of age and prognostic subgroups, to explore the expression and functional role of ferritin in AML cells as well as the regulation of serum ferritin levels in AML patients.
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Keywords: FTH1; FTL; acute myeloid leukemia; chemoresistance; dexamethasone; ferritin; glucocorticoids; inflammation; leukemic stem cells

Document Type: Research Article

Publication date: February 1, 2019

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