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Impact of atrial fibrillation on platelet gene expression

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Platelets retain cytoplasmic messenger RNA and are capable of protein biosynthesis. Several diseases are known to impact the platelet transcriptome but the effect of non‐valvular atrial fibrillation (NVAF) on platelet RNA transcript is essentially unknown. The aim of this study was to evaluate the impact of NVAF on platelet RNA transcript by measuring platelet genes expression in consecutive NVAF patients before and 3‐4¬†months after pulmonary vein isolation (PVI) and compared to normal sinus rhythm controls (NSR).
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Keywords: gene expression; platelets; pulmonary vein isolation; thrombosis

Document Type: Research Article

Publication date: June 1, 2017

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