Complex MLL rearrangement in non‐infiltrated bone marrow in an infant with stage II precursor B‐lymphoblastic lymphoma
Precursor B‐lymphoblastic lymphoma cells are indistinguishable by morphology, and immune phenotype from lymphoblasts in acute leukemia which in infancy is associated with MLL rearrangements and a poor prognosis. The role of MLL gene deregulation in rare cases of isolated lymphoblastic lymphoma in infants is obscure. We report the case of a 10‐month‐old child who presented with a cutaneous nodule on the left foot. Histological diagnosis was precursor B‐lymphoblastic lymphoma. The young age of the patient motivated us to investigate the presence of an MLL rearrangement.
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