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Aspirin inhibits proliferation and induces apoptosis of multiple myeloma cells through regulation of Bcl‐2 and Bax and suppression of VEGF

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Aspirin (ASA) has been frequently used for thromboprophylaxis in patients with multiple myeloma (MM) when treated with thalidomide or lenalidomide. Despite the well‐recognized chemopreventive role of ASA in some solid tumors particularly for colon cancer, whether ASA displays the antimyeloma activity remains unclear.
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Keywords: Bax; Bcl‐2; VEGF; apoptosis; aspirin; multiple myeloma; proliferation

Document Type: Research Article

Publication date: October 1, 2014

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