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Rapid remineralization of multiple disseminated bone lesions after high‐dose cytarabine in a patient with isolated myeloid sarcoma

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Isolated myeloid sarcoma is a rare presentation of acute myeloid leukemia. There are limited data available concerning the prognostic relevance and the right treatment strategy for this clinical scenario. Here, we report a case of acute myeloid leukemia with extensive lesions and fractures in multiple bones in a 64‐yr‐old male patient. Remarkably, treatment with a high‐dose cytarabine regimen led to rapid remineralization of all bone lesions and recovery of the patient's mobility within a few weeks. Thereby, surgical treatment and radiotherapy could be avoided, supporting the role of intensive induction and standard consolidation chemotherapy as first‐line treatment for myeloid sarcoma.
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Keywords: extramedullary AML; myeloid sarcoma; treatment

Document Type: Research Article

Publication date: June 1, 2014

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