Skip to main content
padlock icon - secure page this page is secure

Complete donor chimaerism of Langerhans cells in lymph node early after allogeneic bone marrow transplantation

Buy Article:

$59.00 + tax (Refund Policy)

Ikeda K, Shichishima T, Teshima T, Ogawa K, Nakamura-Shichishima A, Tajima H, Noji H, Hashimoto Y, Takeyama K, Ishibashi T, Ohto H, Abe M, Maruyama Y. Complete donor chimaerism of Langerhans cells in lymph node early after allogeneic bone marrow transplantation.

Eur J Haematol 2006. © Blackwell Munksgaard 2006. Abstract: 

Host-derived Langerhans cells (LCs) are crucial antigen-presenting cells that cause graft-vs.-host disease after allogeneic haematopoietic stem cell transplantation (HSCT). However, chimaerism of LCs after allogeneic HSCT is largely unknown in humans. We here report a case that developed dermatopathic lymphadenitis accompanied by an accumulation of donor-derived LCs in the second month after allogeneic HSCT with reduced-intensity conditioning. This is the first case to show that donor LCs have the ability to migrate into draining lymph nodes and replace host LCs early after HSCT in humans.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Langerhans cell; chimaerism; dendritic cell; haematopoietic stem cell transplantation; reduced-intensity conditioning; turnover

Document Type: Research Article

Affiliations: 1: First Department of Internal Medicine 2: Center for Cellular and Molecular Medicine, Kyushu University, Fukuoka 3: First Department of Pathology, Fukushima Medical University, Fukushima, Japan 4: Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University, Fukushima

Publication date: March 1, 2006

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more