Skip to main content
padlock icon - secure page this page is secure

Successful treatment with splenectomy and interferon alpha against recurred hemophagocytic syndrome in remission state of anaplastic large cell lymphoma following high-dose therapy and autologous peripheral blood stem cell transplantation

Buy Article:

$59.00 + tax (Refund Policy)

Cho SG, Koh YB, Chang HS, Park G, Kang CS, Park JW, Min WS. Successful treatment with splenectomy and interferon alpha against recurred hemophagocytic syndrome in remission state of anaplastic large cell lymphoma following high-dose therapy and autologous peripheral blood stem cell transplantation.

Eur J Haematol 2005: 74: 259–262. © Blackwell Munksgaard 2005. Abstract: 

A 25-yr-old man had been diagnosed as having CD30+ anaplastic large cell lymphoma associated with hemophagocytic syndrome (HS). He received aggressive frontline chemotherapies and consolidation with autologous peripheral blood stem cell transplantation (PBSCT) following high-dose chemotherapy combined with splenic irradiation (720 cGy in fraction of 180 cGy). However, HS recurred on day 50 of PBSCT without radiologic evidence of lymphoma relapse. On day 56 of PBSCT, splenectomy was performed and pathology showed massive sinusoidal infiltration of histiocytes. On day 68 of PBSCT, administration of interferon alpha was started and maintained for 24 months. HS was completely resolved and he has been alive well and in complete remission (CR) , 60 months after initial diagnosis.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: anaplastic large cell lymphoma; autologous PBSCT; hemophagocytic syndrome; interferon alpha; splenectomy

Document Type: Research Article

Affiliations: 1: Hematology 2: Surgery 3: Radiation Oncology 4: Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Publication date: March 1, 2005

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more