Skip to main content
padlock icon - secure page this page is secure

Inflammatory pseudotumor of the spleen with EBV positivity: report of a case

Buy Article:

$47.00 + tax (Refund Policy)

Oz Puyan F, Bilgi S, Unlu E, Yalcin O, Altaner S, Demir M, Cakir B. Inflammatory pseudotumor of the spleen with EBV positivity: report of a case.

Eur J Haematol 2004: 72: 285–291. © Blackwell Munksgaard 2004. Abstract:

Inflammatory pseudotumor (IPT) of the spleen is a rare benign tumor with unknown etiology. It causes problems in the diagnosis because of mimicking some hematopoetic malignancies. Here we report the case of a 36-yr-old woman complaining of nausea and insomnia. Laboratory investigations were limited to increase of leukocyte and thrombocyte count. Ultrasonography and magnetic resonance (MR) imaging showed circumscribed solid lobulated mass, measuring about 6.5 cm in diameter, located in the dorsal region of the spleen. Splenectomy was performed with the differential diagnosis including hamartoma and lymphoma of the spleen. Histological examination of the sharply demarcated splenic mass consisted of myofibroblasts and admixture of inflammatory cells. Immunohistochemistry and in situ hybridization were performed. IPT of the spleen was diagnosed. Epstein–Barr virus (EBV) was detected in the tumor by in situ hybridization. This rare entity is presented because of its clinical, radiological and pathological difficulties in the differential diagnosis.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Epstein–Barr virus; differential diagnosis; inflammatory pseudotumor; spleen

Document Type: Research Article

Affiliations: 1: Department of Pathology 2: Department of Radiology 3: Internal Medicine Division of Haematology, Trakya University Medical Faculty, Edirne, Turkey

Publication date: 01 April 2004

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more