Skip to main content
padlock icon - secure page this page is secure

Open Access Ruthenium Polyaminocarboxylate Complexes

Download Article:
(HTML 75.4 kb)
(PDF 925.6 kb)
Ruthenium (Ru) complexes containing polyaminocarboxylate (pac) ligands (Ru-pac) have features which indicate they may be suitable for biological applications. For instance, Ru-pac complexes can bind to biomolecules through a rapid and facile aquo-substitution reaction, and Ru-pac has a range of accessible oxidation states. Ru-pac also has some notable catalytic properties that mimic enzymatic hydrocarbon oxidation by cytochrome P-450 in homogeneous conditions. This is of immense significance towards developing Ru-pac based agents for oxidative cleavage of DNA and artificial nuclease in DNA foot-printing experiments. This review aims to highlight the scope of Ru-pac complexes as metallopharmaceuticals, and outlines their potential for certain biological applications.

71 References.

No Supplementary Data.
No Article Media
No Metrics

Document Type: Research Article

Publication date: January 1, 2006

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more