Skip to main content
padlock icon - secure page this page is secure

Impact of postoperative complications on long‐term outcome of curative resection for hepatocellular carcinoma

The full text article is not available for purchase.

The publisher only permits individual articles to be downloaded by subscribers.


The aim of this retrospective study was to determine the impact of postoperative complications on the long‐term outcome of curative liver resection for hepatocellular carcinoma (HCC).


A total of 863 patients who had curative resection of HCC from December 1989 to December 2004 were included in the analysis. Median follow‐up was 35·6 months.


Some 288 patients (33·4 per cent) developed postoperative complications. The hospital mortality rate was 5·3 per cent (46 patients). Multiple logistic regression analysis showed that older age and massive intraoperative blood loss were related to a significantly higher complication rate. Demographics of patients with and without postoperative complications were comparable. The former had significantly more blood loss (median 1·1 versus 0·7 litres; P < 0·001) and required more transfused blood (P < 0·001). The overall survival rates of patients without complications at 1, 3, 5 and 10 years were 83·6, 62·8, 51·5 and 32·1 per cent respectively. Corresponding rates for those with complications were 67·8, 52·4, 41·5 and 26·6 per cent (P = 0·004). Cox proportional hazard model analysis revealed that the presence of postoperative complications was independently associated with poor overall survival.


Postoperative complications can affect overall long‐term survival after resection of HCC. Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Document Type: Research Article

Publication date: January 1, 2009

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more