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Enucleation of pancreatic neoplasms

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Standard resections for benign and borderline neoplasms of the pancreas are associated with a significant risk of long‐term functional impairment, whereas enucleation preserves healthy parenchyma and pancreatic function. The aim of this study was to evaluate postoperative and long‐term oncological and functional results after pancreatic enucleation.


Data collected prospectively from 61 consecutive patients who underwent pancreatic enucleation were analysed.


There were no deaths. A clinically significant pancreatic fistula was reported in 14 patients (23 per cent), and five patients (8 per cent) had a further operation for fistula‐related complications. The most common indication for surgery was endocrine neoplasm (38 patients; 62 per cent) and two patients (3 per cent) had a final histopathological diagnosis of malignant neoplasm. At a median follow‐up of 61 months no patient had developed tumour recurrence or exocrine insufficiency. Two elderly patients developed non‐insulin‐dependent diabetes.


Enucleation is an effective procedure for the radical treatment of benign and borderline neoplasms of the pancreas, with good long‐term outcomes. Copyright © 2007 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
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Document Type: Research Article

Publication date: October 1, 2007

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