Population-based study of cancer risk and relative survival following sphincterotomy for stones in the common bile duct
Methods A total of 992 patients was identified and they were followed by linkage to the Swedish Death Registry and the Swedish Cancer Registry.
Results At 1 year or more after sphincterotomy there was no increased risk of cancer in the liver, gallbladder, bile duct or pancreas (standardized incidence ratio 0·80, 95 per cent confidence interval 0·3-1·9). Relative survival was lowered slightly in the first year after sphincterotomy, but did not differ from that of the background population thereafter.
Conclusion Endoscopic sphincterotomy for stones in the common bile duct does not appear to affect the risk of cancer in the pancreas, liver or bile ducts, nor does it affect long-term survival.
Document Type: Research Article
Affiliations: 1: Cancer Epidemiology, University Hospital, Uppsala, Sweden 2: Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA 3: Departments of Surgery
Publication date: September 1, 1997