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Open Access One size does not fit all: community views on choices for TB treatment and prevention

This article is Open Access under the terms of the Creative Commons CC BY licence.

Treatment and prevention paradigms in TB have been dominated by a ‘one-size-fits-all’ approach, in which all persons are given the same treatment regimens. This stands in contrast to other health conditions, where differentiated models of care have been shown to be effective. In this Viewpoint, we make the case for considering multiple factors when deciding which regimens should be offered to people with TB infection and disease. Choice about which regimens to use should be made in conjunction with people who have TB and consider efficacy, safety, duration, pill burden, formulation, drug interactions, time spent in monitoring, drug susceptibility, compatibility with other areas of life, and availability of support services. Ideally, these choices should be considered within an equity framework with the most intensified services being offered to those considered most vulnerable.

Keywords: community views; differentiated care delivery; treatment options; tuberculosis

Document Type: Research Article

Affiliations: 1: Stellenbosch University, Cape Town, South Africa;, Global TB Community Advisory Board, New York, NY, USA; 2: Global TB Community Advisory Board, New York, NY, USA;, Access to Rights and Knowledge Foundation, Kohima 3: Global TB Community Advisory Board, New York, NY, USA;, Survivors Against TB, New Delhi, India; 4: Global TB Community Advisory Board, New York, NY, USA;, Treatment Action Group, New York, NY; 5: Global TB Community Advisory Board, New York, NY, USA;, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, USA; 6: Global TB Community Advisory Board, New York, NY, USA; 7: Global TB Community Advisory Board, New York, NY, USA;, Moldova National Association of Tuberculosis Patients “SMIT” (Society of Moldova against Tuberculosis), Chis¸ina˘u, Moldova; 8: Global TB Community Advisory Board, New York, NY, USA;, Department of Anthropology, Wayne State University, Detroit, MI, USA

Publication date: September 21, 2023

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