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Home / Public Health Action, Volume 4, Number 2

Open Access Decline in national tuberculosis notifications with national scale-up of antiretroviral therapy in Malawi

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From 2000 to 2012, Malawi scaled up antiretroviral therapy (ART) from <3000 to 404 905 persons living with HIV/ AIDS (human immunodeficiency virus/acquired immune-deficiency syndrome), representing an ART coverage of 40.6% among those living with HIV. During this time, annual tuberculosis (TB) notifications declined by 28%, from 28 234 to 20 463. Percentage declines in annual TB case notifications were as follows: new TB (26%), recurrent TB (40%), new smear-positive pulmonary TB (19%), new smear-negative pulmonary TB (42%), extra-pulmonary TB (19%), HIV-positive TB (30%) and HIV-negative TB (10%). The decline in TB notifications is associated with ART scale-up, supporting its value in controlling TB in high HIV prevalence areas in sub-Saharan Africa.
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Keywords: ART; HIV/AIDS; Malawi; TB; recurrent TB

Document Type: Research Article

Affiliations: 1: National Tuberculosis Control Programme, Community Health Science Unit, Lilongwe, Malawi 2: Department of HIV and AIDS, Ministry of Health, Lilongwe, Malawi 3: International Union against Tuberculosis and Lung Disease, Paris, France, London School of Hygiene & Tropical Medicine, London, UK 4: Medical Department, Operational Centre Brussels, Médecins Sans Frontières, MSF-Luxembourg, Luxembourg 5: Department of HIV and AIDS, Ministry of Health, Lilongwe, Malawi, International Training and Education Center for Health, Lilongwe, Malawi and University of Washington, Seattle, Washington, USA

Publication date: 21 June 2014

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  • Public Health Action (PHA), The Union's quarterly Open Access journal, welcomes the submission of articles on operational research. It publishes high-quality scientific research on health services, providing new knowledge on how to improve access, equity, quality and efficiency of health systems and services.

    The Editors will consider any manuscript reporting original research on quality improvements, cost-benefit analysis, legislation, training and capacity building, with a focus on all relevant areas of public health (e.g. infection control, nutrition, TB, HIV, vaccines, smoking, COVID-19, microbial resistance, outbreaks etc).

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