Adaptation and validation of perceived HIV and TB stigma scales among persons with TB
Stigma is a barrier to care for people affected by TB and HIV in Uganda, where these conditions remain endemic. While scales have been adapted and validated to measure stigma among TB-affected households in Uganda, there is a need for scales that measure the experiences of persons with TB (PWTB).
We adapted the Van Rie 12-item individual perspectives TB scale and 10-item individual perspectives HIV scale for use in Uganda through cross-cultural discussions with a multidisciplinary research team and four cognitive interviews with community health workers and PWTB. We then conducted a cross-sectional study administering each scale to 125 PWTB. We performed exploratory factor analysis, evaluated internal validity, and assessed convergent validity with perceived social support.
Exploratory factor analysis yielded a one-factor solution for both scales, with marginal model fit (standardised root mean square residual = 0.09 for TB, = 0.07 for HIV). There was evidence of convergent validity through a positive correlation of the TB (r = 0.22, p = 0.01) and HIV stigma (r = 0.22, p = 0.01) scales with perceived social support. Both scales had good internal validity (Cronbach’s α = 0.86 for TB, = 0.87 for HIV).
Adapted scales to measure perceived HIV and TB stigma among PWTB in Uganda demonstrated promising psychometric properties by removing one and two items, respectively.
Keywords: Kampala; Uganda; co-infection; psychometrics; scale
Document Type: Research Article
Affiliations: 1: Yale School of Medicine, New Haven, USA;, Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, USA;, Uganda Tuberculosis Implementation Research Consortium, Makerere University, Kampala, Uganda; 2: Uganda Tuberculosis Implementation Research Consortium, Makerere University, Kampala, Uganda; 3: Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, USA;, Uganda Tuberculosis Implementation Research Consortium, Makerere University, Kampala, Uganda;, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; 4: Department of Social and Behavioral Sciences, Yale School of Public Health, New Haven, USA; 5: Uganda Tuberculosis Implementation Research Consortium, Makerere University, Kampala, Uganda;, Center for Interdisciplinary Research on AIDS, Yale University, New Haven, CT;, Department of Social & Behavioral Sciences, New York University School of Global Public Health, New York, NY, USA;, Department of Epidemiology, New York University School of Global Public Health, New York, NY, USA; 6: Uganda Tuberculosis Implementation Research Consortium, Makerere University, Kampala, Uganda;, Clinical Epidemiology Unit, Department of Medicine, Makerere University, Kampala, Uganda; 7: Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, USA;, Uganda Tuberculosis Implementation Research Consortium, Makerere University, Kampala, Uganda;, Center for Interdisciplinary Research on AIDS, Yale University, New Haven, CT;, Pulmonary, Critical Care, and Sleep Medicine Section, Yale School of Medicine, New Haven, CT, USA;, Center for Methods in Implementation and Prevention Science, Yale School of Public Health, New Haven, CT, USA.
Publication date: March 1, 2025
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