Health-related quality of life associates with clinical parameters in patients with NTM pulmonary disease
METHODS: We performed a single-centre, cross-sectional, retrospective study of 101 patients with NTM-PD from December 2016 to October 2019. The relationship between the SGRQ scores and clinical parameters was evaluated.
RESULTS: The median patient age was 67.0 years. Pulmonary function, radiological score, albumin levels, C-reactive protein levels and incremental shuttle walk test distance (ISWD) were significantly correlated with the total and component scores on the SGRQ. Multiple regression analysis showed that the SGRQ score was significantly associated with radiological score, pulmonary function and ISWD.
CONCLUSION: This study was the first to assess the effect of clinical parameters on the SGRQ in patients with NTM-PD. HRQoL as determined using the SGRQ was associated with the radiological score, pulmonary function and ISWD in patients with NTM-PD.
Keywords: HRQoL; St George´s Respiratory Questionnaire; exercise tolerance; non-tuberculous mycobacterial pulmonary disease; pulmonary function; radiological score
Document Type: Research Article
Affiliations: 1: Department of Clinical Mycobacteriology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, Respiratory Care and Rehabilitation Center, Fukujuji Hospital, Japan Anti-Tuberculosis Association (JATA), Tokyo, Japan 2: Respiratory Care and Rehabilitation Center, Fukujuji Hospital, Japan Anti-Tuberculosis Association (JATA), Tokyo, Japan 3: Respiratory Diseases Center, Fukujuji Hospital, JATA, Tokyo, Japan, Department of Basic Mycobacteriology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan 4: Respiratory Diseases Center, Fukujuji Hospital, JATA, Tokyo, Japan 5: Respiratory Diseases Center, Fukujuji Hospital, JATA, Tokyo, Japan, Division of Clinical Research, Fukujuji Hospital, JATA, Tokyo, Japan 6: Department of Clinical Mycobacteriology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, Respiratory Care and Rehabilitation Center, Fukujuji Hospital, Japan Anti-Tuberculosis Association (JATA), Tokyo, Japan, Respiratory Diseases Center, Fukujuji Hospital, JATA, Tokyo, Japan
Publication date: April 1, 2021
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