Epidemiological and spatial factors for tuberculosis: a matched case-control study in Nagata, Japan
DESIGN: A hospital-based case-control study using medical records was conducted. A total of 103 age- and sex-matched TB patients (cases) and 299 patients without TB (controls) were recruited from January 2000 to December 2016 in a hospital in Nagata, Kobe, Japan. Logistic regression, kernel density estimation, Cross L function and a Poisson regression model were applied.
RESULTS: The epidemiological factors associated with TB were being a health care worker (OR 10.1) and lower serum albumin level (OR 0.5). Spatial analyses revealed TB to be positively associated with population density (risk ratio [RR] 32.1), the proportion of single households (RR −1.85) and persons aged 65 years (RR 2.65) and one spatial clustering.
CONCLUSION: Our findings could help in the identification of high TB risk individuals and districts.
Document Type: Research Article
Affiliations: 1: Department of Public Health, Graduate School of Health Sciences, Kobe University, Hyogo 2: Department of Internal Medicine, Kobe Kyodo Hospital, Hyogo, Japan
Publication date: February 1, 2019
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