Cost of point-of-care lateral flow urine lipoarabinomannan antigen testing in HIV-positive adults in South Africa
METHODS: We estimated the costs of using LF-LAM in HIV-positive adults with CD4 counts 150 cells/μl enrolled in the TB Fast Track Trial in South Africa. We also estimated costs of POC haemoglobin (Hb), as this was used in the study algorithm. Data on clinic-level (10 intervention clinics) and above-clinic-level costs were collected.
RESULTS: A total of 1307 LF-LAM tests were performed at 10 clinics over 24 months. The mean clinic-level costs were US$12.80 per patient for LF-LAM and POC Hb; LF-LAM costs were US$11.49 per patient. The mean above-clinic-level unit costs for LF-LAM were US$12.06 for clinic preparation, training, coordination and mentoring. The mean total cost of LF-LAM was US$23.55 per patient.
CONCLUSION: At clinic level, the cost of LF-LAM was comparable to other TB diagnostics in South Africa. It is important to consider above-clinic-level costs for POC tests, as these may be required to support roll-out and ensure successful implementation.
Keywords: South Africa; coinfection; diagnostic tests; point-of-care systems; tuberculosis
Document Type: Research Article
Affiliations: 1: Aurum Institute, Johannesburg 2: Aurum Institute, Johannesburg, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa 3: TB Centre, London School of Hygiene & Tropical Medicine, London, UK 4: School of Public Health, University of the Witwatersrand, Johannesburg, South Africa, TB Centre, London School of Hygiene & Tropical Medicine, London, UK, Africa Health Research Institute, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa
Publication date: September 1, 2018
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