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Free Content Economic burden of multidrug-resistant tuberculosis: a multicenter study across Vietnamese regions

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SETTING: Multidrug-resistant tuberculosis (MDR-TB) has become a major worldwide health problem. Various studies have been conducted on the cost of MDR-TB treatment; however, this has remained largely unexplored in Viet Nam.

OBJECTIVE: To estimate the total cost of MDR-TB treatment at several health care facilities in Viet Nam.

DESIGN: A prospective, prevalence-based study was conducted at three selected centers from March to June 2016 in 204 patients, 102 of whom were treated for 9 months and 102 for 20 months. Direct medical costs were calculated using electronic hospital databases, while a questionnaire was used to interview participants for evaluating direct non-medical and indirect costs. Total costs were estimated from a societal perspective in 2017 USD.

RESULTS: Patients were mostly males aged 25–44 years. The average length of hospitalization in the 9-month treatment group was 168 ± 127 days; in the 20-month group, it was 671 ± 119 days. The average treatment cost for MDR-TB was respectively US$1480.34 ± 211.61 and US$2695.58 ± 294.98 for the 9- and 20-month treatment groups. Direct medical costs generally accounted for the highest proportion of the total costs, while the cost of pharmaceuticals and materials comprised the highest direct cost.

CONCLUSION: There was a significant difference in total costs among the three hospitals in the 9- and 20-month treatment groups.
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Keywords: MDR-TB; Viet Nam; cost of illness; multidrug-resistant tuberculosis; treatment

Document Type: Research Article

Affiliations: 1: Graduate Program in Social, Economic and Administrative Pharmacy, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand, Viet Namese National Tuberculosis Program, Ha Noi 2: Viet Namese National Tuberculosis Program, Ha Noi 3: Department of Pharmacy Administration, Faculty of Pharmacy, University of Medicine and Pharmacy, Ho Chi Minh City 4: Department of Health Insurance, Ministry of Health, Ha Noi, Viet Nam 5: Department of Epidemiology, Faculty of Public Health, Mahidol University, Bangkok 6: Graduate Program in Social, Economic and Administrative Pharmacy, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand, Social Administrative Pharmacy Excellence Research Unit, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand

Publication date: August 1, 2018

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on lung health world-wide.

    To share scientific research of immediate concern as rapidly as possible, The Union is fast-tracking the publication of certain articles from the IJTLD and publishing them on The Union website, prior to their publication in the Journal. Read fast-track articles.

    Certain IJTLD articles are also selected for translation into French, Spanish, Chinese or Russian. These are available on the Union website.

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