Depression among multidrug-resistant tuberculosis patients in Punjab, Pakistan: a large cross-sectional study
DESIGN: This cross-sectional study analysed health care service data from 12 treatment sites following a single screening event using the Patient Health Questionnaire 9 (PHQ-9). Logistic regression models were used to identify associations.
RESULTS: Data were collected from 1279 patients with MDR-TB. The proportion of MDR-TB patients with depression was 42.8% (95%CI 40.1–45.5). Rates of depression varied according to duration of treatment, with the highest proportion (53.2%) found in those who were in months 10–12 of treatment. The odds of depression in women were higher than for men (adjusted odds ratio [aOR] 1.84, 95%CI 1.46–2.33). The odds of depression were higher in patients living in concrete-built houses than in those living in mud-built houses (aOR 1.37, 95%CI 1.03–1.82).
CONCLUSION: Depression is common in MDR-TB patients, and should be screened for and treated within MDR-TB treatment programmes.
Keywords: depression; drug resistance; epidemiology; tuberculosis
Document Type: Research Article
Affiliations: 1: Nuffield Centre for International Health and Development, University of Leeds, Leeds, UK 2: Association for Social Development, Islamabad 3: National TB Control Programme Islamabad, Pakistan
Publication date: July 1, 2018
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