@article {Castro:2016:1027-3719:926, title = "Estimating tuberculosis cases and their economic costs averted in the United States over the past two decades", journal = "The International Journal of Tuberculosis and Lung Disease", parent_itemid = "infobike://iuatld/ijtld", publishercode ="iuatld", year = "2016", volume = "20", number = "7", publication date ="2016-07-01T00:00:00", pages = "926-933", itemtype = "ARTICLE", issn = "1027-3719", eissn = "1815-7920", url = "https://www.ingentaconnect.com/content/iuatld/ijtld/2016/00000020/00000007/art00016", doi = "doi:10.5588/ijtld.15.1001", keyword = "low-incidence country, TB, public health benefits and costs, United States", author = "Castro, K. G. and Marks, S. M. and Chen, M. P. and Hill, A. N. and Becerra, J. E. and Miramontes, R. and Winston, C. A. and Navin, T. R. and Pratt, R. H. and Young, K. H. and LoBue, P. A.", abstract = "BACKGROUND: Following a concerted public health response to the resurgence of tuberculosis (TB) in the United States in the late 1980s, annual TB incidence decreased substantially. However, no estimates exist of the number and cost savings of TB cases averted.METHODS: TB cases averted in the United States during 19952014 were estimated: Scenario 1 used a static 1992 case rate; Scenario 2 applied the 1992 rate to foreign-born cases, and a pre-resurgence 5.1% annual decline to US-born cases; and a statistical model assessed human immunodeficiency virus and TB program indices. We applied the cost of illness to estimate the societal benefits (costs averted) in 2014 dollars.RESULTS: During 19922014, 368184 incident TB cases were reported, and cases decreased by two thirds during that period. In the scenarios and statistical model, TB cases averted during 19952014 ranged from approximately 145000 to 319000. The societal benefits of averted TB cases ranged from US$3.1 to US$6.7 billion, excluding deaths, and from US$6.7 to US$14.5 billion, including deaths.CONCLUSIONS: Coordinated efforts in TB control and prevention in the United States yielded a remarkable number of TB cases averted and societal economic benefits. We illustrate the value of concerted action and targeted public health funding.", }