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Free Content Tuberculosis treatment outcomes among peri-urban children receiving doorstep tuberculosis care

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OBJECTIVE: To determine the optimal tuberculosis (TB) management strategy for children living in peri-urban, resource-limited settings.

DESIGN: We compared TB treatment outcomes among children aged 0–15 years receiving doorstep care (n = 82) with those of a historical group (n = 97) receiving clinic-based care.

RESULTS: The doorstep care and clinic-based groups had similar age and sex profiles; treatment default rates were 3.7% (3/82) vs. 38.1% (37/97, P < 0.0001), treatment completion rates were 65.9% (54/82) vs. 51.6% (50/97, P = 0.01), and cure rates were 13.4% (11/82) vs. 2.1% (2/97), respectively (P < 0.0001).

CONCLUSION: Children living in peri-urban communities had improved TB treatment outcomes with doorstep care.
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Keywords: South Africa; TB; doorstep care; peri-urban; tuberculosis

Document Type: Research Article

Affiliations: 1: *Centre for the AIDS Programme of Research in South Africa (CAPRISA) 2: *Centre for the AIDS Programme of Research in South Africa (CAPRISA), Medical Research Council CAPRISA HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

Publication date: February 1, 2016

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on lung health world-wide.

    To share scientific research of immediate concern as rapidly as possible, The Union is fast-tracking the publication of certain articles from the IJTLD and publishing them on The Union website, prior to their publication in the Journal. Read fast-track articles.

    Certain IJTLD articles are also selected for translation into French, Spanish, Chinese or Russian. These are available on the Union website.

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