Tuberculosis is frequently diagnosed within 12 months of diabetes mellitus
OBJECTIVE: To investigate trends in TB incidence among newly diagnosed DM patients.
DESIGN: A retrospective cohort study of the claims database of the Health Insurance Review and Assessment Service in Korea was performed. Participants were newly diagnosed with type 2 DM in 2009. The study outcome was TB incidence between 2009 and 2011 among participants according to duration of type 2 DM.
RESULTS: A cohort of 331 601 patients with newly diagnosed type 2 DM in 2009 was identified. During the 3-year follow-up period, 1533 patients were diagnosed with TB. The estimated incidence of TB among newly diagnosed type 2 DM patients was 18/10 000 patient-years (py) (95%CI 17.5–19.4). TB incidence was 33/10 000 py (95%CI 30.0–35.6) in the first 6 months, and 19/10 000 py (95%CI 16.5–20.6) in the following 6-month period.
CONCLUSIONS: The risk of developing TB was increased among DM patients, particularly during the first 12 months after DM diagnosis.
Document Type: Research Article
Affiliations: 1: Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea 2: Medical Research Collaborating Center, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea; Institute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea 3: Medical Research Collaborating Center, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea 4: Department of Social & Preventive Medicine, Inha University School of Medicine, Incheon, Republic of Korea 5: Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea 6: Department of Internal Medicine, Severance Hospital, Institute of Chest Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea
Publication date: September 1, 2015
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