Skip to main content

Risk factors associated with recent transmission of tuberculosis: systematic review and meta-analysis [Review article]

Buy Article:

$34.78 + tax (Refund Policy)

A systematic review of published articles was performed to identify risk factors associated with recent transmission of tuberculosis (TB). The computerized search identified studies in PubMed, Ovid, CDSR, CINAHL and EMBASE published between 1994 and 2005. Of 137 articles, 30 satisfied all the inclusion criteria for meta-analysis. A random effects model estimated the odds ratio (OR), confidence interval (CI), and heterogeneity between studies. Recent transmission of TB was associated with: ethnic minority (OR 3.03, 95%CI 2.21– 4.16), being a native of the country (OR 2.33, 95%CI 1.76–3.08), residing in an urban area (OR 1.52, 95%CI 1.35–1.72), drug use (OR 3.01, 95%CI 2.14–4.22), excessive alcohol consumption (OR 2.27, 95%CI 1.69–3.06), homelessness (OR 2.87, 95%CI 2.04–4.02), previous incarceration (OR 2.21, 95%CI 1.71–2.86), human immunodeficiency virus infection/acquired immune-deficiency syndrome (OR 1.66, 95%CI 1.36–2.05), young age (OR 2.09, 95%CI 1.69–2.59), sputum smear positivity (OR 1.39, 95%CI 1.20–1.60) and male sex (OR 1.37, 95%CI 1.19–1.58). The results should be useful for improving prevention and control strategies, thus contributing to a reduction in Mycobacterium tuberculosis transmission.

Keywords: molecular epidemiology; risk factors; transmission; tuberculosis

Document Type: Review Article

Affiliations: 1: Centro de Investigación de Enfermedades Tropicales (CIET), Universidad Autónoma de Guerrero, Acapulco, Guerrero, México 2: Division of Infectious Diseases, School of Public Health, University of California, Berkeley, California, USA 3: Community Information and Epidemiological Technology (CIETcanada), Institute of Population Health, University of Ottawa, Ottawa, Canada 4: Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de Mexico, Mexico DF, México

Publication date: January 1, 2009

More about this publication?
  • The International Journal of Tuberculosis and Lung Disease (IJTLD) is for clinical research and epidemiological studies on lung health, including articles on TB, TB-HIV and respiratory diseases such as COVID-19, asthma, COPD, child lung health and the hazards of tobacco and air pollution. Individuals and institutes can subscribe to the IJTLD online or in print – simply email us at [email protected] for details.

    The IJTLD is dedicated to understanding lung disease and to the dissemination of knowledge leading to better lung health. To allow us to share scientific research as rapidly as possible, the IJTLD is fast-tracking the publication of certain articles as preprints prior to their publication. Read fast-track articles.

  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • International Journal of Tuberculosis and Lung Disease
  • Public Health Action
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content