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Free Content Guidelines for establishing trials of new tests to diagnose tuberculosis in endemic countries

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Efforts to control tuberculosis are currently hampered by the lack of effective tools for the detection of infected individuals. Although new diagnostic tests are being developed and marketed, there is a paucity of data on the value of new technology for the diagnosis of tuberculosis in endemic regions of the world. Trials of new tools need to be undertaken in appropriate settings and to a high standard. The value of previous studies has frequently been compromised by inadequate study design and poor execution. We offer guidelines to assist in planning trials for new tests for the diagnosis of tuberculosis.
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Keywords: diagnosis; technology; trial; tuberculosis

Document Type: Short Communication

Affiliations: 1: Public Health Laboratory Service, Health Protection Agency, Communicable Disease Surveillance Centre, London, UK 2: Department of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK

Publication date: May 1, 2004

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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