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Free Content Clinical and radiographic features of pulmonary tuberculosis in non-AIDS immunocompromised patients

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SETTING: Department of Chest Diseases, Istanbul Faculty of Medicine, Istanbul University.

OBJECTIVE: To determine the clinical and radiographic presentation of pulmonary tuberculosis in non-AIDS immunocompromised patients (ICP).

DESIGN: A retrospective review of medical records of 143 patients (63 immunocompromised patients and 80 immunocompetent patients) with pulmonary tuberculosis from 1992 to 2001.

RESULTS: In ICPs, fever was more frequently observed (84.1% vs. 40%, P = 0.0000002), tuberculosis was more frequently disseminated (23.8 vs. 3.8%, P = 0.0008), and lung infiltrations were more often lobar or segmental consolidation (20.6% vs. 0%, P = 0.00007) and miliary lesions (17.5 vs. 3.8%, P = 0.014) than in the control patients. Hilar and/or mediastinal adenopathy was also more frequently documented in ICPs (14.3% vs. 2.5%, P = 0.01).

CONCLUSION: Fever, atypical chest radiograph and disseminated disease are common findings of pulmonary tuberculosis in ICPs.
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Keywords: immunosuppression; pulmonary tuberculosis; radiology

Document Type: Regular Paper

Affiliations: 1: Department of Pulmonary Diseases, Division of Nephrology, Istanbul Medical School, Istanbul University, Istanbul, Turkey 2: Department of Internal Medicine, Division of Nephrology, Istanbul Medical School, Istanbul University, Istanbul, Turkey

Publication date: 01 August 2003

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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