Double casting prototyping with a thermal aging step for fabrication of 3D microstructures in poly(dimethylsiloxane)
The paper describes a cheap and accessible technique of a poly(dimethylsiloxane) (PDMS) master treatment by thermal aging as a step of double casting microfabrication process. Three-dimensional PDMS microstructures could have been achieved using this technique. It was proved, that thermal aging changes nanotopology of a PDMS surface and thus enhances efficiency of double casting prototyping. The thermally aged PDMS master could have been used for multiple and correct replication of over 98% of the fabricated microstructures. Moreover, lack of chemical modification preserved the biocompatibility of PDMS devices. The fabricated microstructures were successfully utilized for 3D cell culture.
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Document Type: Research Article
Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland
Institute of Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Warsaw, Poland
Publication date: January 1, 2016