Objective: To evaluate the performance of preliminary phytochemical, antioxidant and
antimicrobial activities of Dracaena cinnabari Balf.f. (Agavaceae) (D. cinnabari) resin, collected
from Socotra Island (Yemen).
Methods: The powdered stem resin is extracted with different solvents by using Soxhlet
apparatus and evaluated for antioxidant and antimicrobial activity against three Gram positive
bacteria (Bacillus cereus NCIM 2106, Staphylococcus aureus NCIM 2127, and Micrococcus luteus
NCIM 2169), seven Gram negative bacteria (Escherichia coli NCIM 2924, Pseudomonas aeruginosa
NCIM 2863, Salmonella typhimurium NCIM 2501, Klebsiella aerogenes NCIM 2281, Proteus morganii
NCIM 2860, Escherichia coli dh5α, Escherichia coli CSH) and three fungi (Candida albicans MTCC
227, Aspergillus flavus MTCC 873, Aspergillus niger MTCC 1781).
Results: The antimicrobial activity data revealed that, the selected microorganisms possess
varied sensitivity response to chloroform extract followed by methanol and benzene extract of D.
cinnabari stem resin. The samples also possess a potent DPPH, OH and SO radical scavenging
activity. In addition, the preliminary phytochemical analysis demonstrated the presence of
alkaloids, flavonoids, terpenoids and other organic compounds which could be reason for
antimicrobial activities of D. cinnabari resin.
Conclusions: The present study is strengthened for the discovery and development of new
antioxidant and antimicrobial drugs from D. cinnabari resin which encourage us to continue with
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Document Type: Research Article
Department of Microbiology, School of Life Sciences, S.R.T.M. University, Nanded- 431 606, (MS), India; Department of Microbiology, Taiz University, Yemen
Department of Microbiology, School of Life Sciences, S.R.T.M. University, Nanded- 431 606, (MS), India
January 1, 2013