Epigenetics Regulators of Genomic Imprinting in Mammals
Genomic imprinting is expression of gene’s only one allele in one of homolog chromosome depending on its maternal or paternal origin. A waste number of genes which are under the imprinting effect were identified as it has a key role in mammalian growth. The first three genes which is identified as imprinted are Igf2r, Igf2 and H19 which are first discovered in mouse genome. Over a hundred genes are identified as imprinted in mammals. Most of the imprinted genes are considered as they have a key role in growth and differentiation. In this review, epigenetic regulators of imprinted genes in mammals were mentioned.
Document Type: Research Article
Affiliations: Ondokuz Mayıs Üniversitesi, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümü, 55139 Samsun
Publication date: 01 January 2016
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