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Open Access Analysis of pathogenic bacteria and drug sensitivity on the infants with dacryocystitis

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AIM: To analyze the pathogenic bacteria and drug sensitivity on infants with dacryocystitis and provide the basis for the rational drug use.

METHODS: Lacrimal sac secretions from 83 infants(86 eyes)with dacryocystitis were used to do bacterial cultures and drug sensitivity tests.

RESULTS:In all 86 eyes, specimens of 84 eyes were positive in bacterial culture, and the pathogenic bacteria positive rate was 97.7%. Totally 94 bacterial strains were isolated from lacrimal sac secretions. The positive rates of gram-positive bacteria were 71.3%(67 strains)and gram-positive bacteria were sensitive to rifampicin, levofloxacin and chloramphenicol. The positive rates of gram-negative bacteria were 28.7%(27 strains), and gram-negative bacteria were sensitive to levofloxacin, chloramphenicol, fusidic acid and ceftazidime.

CONCLUSION: Gram-positive bacteria are the preponderant pathogenic bacteria of dacryocystitis in infants, and the most common of which are streptococcus viridans and staphylococcus epidermidis. The results of drug sensitivity tests show that drug resistance rate of gram-positive bacteria are higher than that of gram-negative bacteria. Levofloxacin and chloramphenicol are effective to infants with dacryocystitis.

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Document Type: Research Article

Affiliations: Shaanxi Institute of Ophthalmology, Shaanxi Key Laboratory of Ophthalmology, Xi'an No.1 Hospital, Xi'an 710002, Shaanxi Province, China

Publication date: 01 January 2015

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