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<&59;p>&59;Entre los años 2007 y 2009, varios estudios epidemiológicos sobre la Insuficiencia Renal Aguda (IRA), mostraron que la enfermedad tiene características clínicas y pronóstico distinto y más severo que los considerados previamente. Otras investigaciones, realizadas entre los años 2010 y 2014, confirmaron y extendieron esos hallazgos. Tomados en conjunto y con la perspectiva de los estudios posteriores, el resultado de los iniciales ha cambiado los paradigmas de la In- suficiencia Renal Aguda y el manejo de los pacientes. Los estudios más recientes sugieren que el pronóstico de la enfermedad puede estar mejorando, posiblemente como consecuencia del mejor manejo de la enfermedad. El autor fue coinvestigador y dirigió una de las tres entidades que participaron en los estudios originales.<&59;/p>&59;<&59;p>&59;<&59;strong>&59;A CHANGE IN THE PARADIGMS OF THE ACUTE RENAL FAILURE<&59;/strong>&59;<&59;/p>&59;<&59;p>&59;<&59;strong>&59;ABSTRACT<&59;/strong>&59;<&59;/p>&59;<&59;p>&59;Between the years of 2007 and 2009 several epidemiologic studies on Acute Renal Failure showed that the disease has clinical features and prognosis different from the predominating beliefs at the time. Rather than having a benign prognosis after recovery, Acute Renal Failure has a high mortality and a guarded prognosis, with frequent development of progressive chro- nic Kidney Disease and the need for maintenance hemodialysis after apparent recovery. The recommendation was made that these patients be closely followed by a nehrologist after leaving the Hospital. Several other studies between 2010 and 2014 confirmed and extended these findings. Taken as a whole, and with the added information of later publications, these studies have changed the paradigm of Acute Renal failure and the management of patients with that disease. The most recent studies suggest that the disease prognosis may be improving, in part at least as a consequence of the better and more insightful management of the disease. The author was a co-investigator and directed one of the three entities that participated in the original studies.<&59;/p>&59;<&59;p>&59; <&59;/p>&59;
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Document Type: Research Article

Affiliations: Universidad de California

Publication date: January 1, 2016

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