Clinical Analysis of Transcatheter Embolotherapy for Congenital Pulmonary Arteriovenous Fistulas in Children
Method: We retrospectively reviewed nine patients with PAVF who underwent transcatheter embolotherapy in the Children’s Hospital of Chongqing Medical University from July 2004 to July 2019, including the demographic characteristics, clinical manifestations, efficiency of closure, and follow-up.
Results: Transcatheter embolotherapy was successful in all cases, and the symptom remission rate was 100% during the follow-up. No residual shunts or other complications occurred during the follow-up period. Compared with before embolotherapy, there were significant changes in the percentage of saturated oxyhemoglobin and total hemoglobin level at the last follow-up (t=10.06, P=0.000; t=3.055, P=0.0076). No significant difference was observed in pulmonary artery pressure before and after embolotherapy (t=0.13, P=0.90).
Conclusions: Transcatheter embolotherapy offers the advantages of safety, with a decreased risk of trauma and a specific effect of treatment, and therefore is recommended as the first-line treatment for congenital PAVFs in children. However, continued research is necessary to understand the full potential of transcatheter embolotherapy.
Document Type: Research Article
Affiliations: 1: Department of Cardiology, The Children’s Hospital of Chongqing Medical University, 136 Zhongshan Er Rold, Yu Zhong District, Chongqing 400014, China 2: The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, China 3: The Children’s Hospital of Chongqing Medical University, 136 Zhongshan Er Rold, Yu Zhong District, Chongqing 400014, China 4: Department of Biomedical Science, Charlie E. Schmidt College of Medicine, Florida Atlantic University, 777 Glades Road, Boca Raton, FL 33431, USA
Publication date: November 1, 2020
This article was made available online on October 21, 2020 as a Fast Track article with title: "Clinical Analysis of Transcatheter Embolotherapy for Congenital Pulmonary Arteriovenous Fistulas in Children".
Cardiovascular Innovations and Applications (CVIA) publishes focused articles and original clinical research that explore novel developments in cardiovascular disease, effective control and rehabilitation in cardiovascular disease, and promote cardiovascular innovations and applications for the betterment of public health globally. The journal publishes basic research that has clinical applicability in order to promote timely communication of the latest insights relating to coronary artery disease, heart failure, hypertension, cardiac arrhythmia, prevention of cardiovascular disease with a heavy emphasis on risk factor modification. Cardiovascular Innovations and Applications is the official journal of the Great Wall International Congress of Cardiology (GW-ICC). It aims to continue the work of the GW-ICC by providing a global scientific communication platform for cardiologists that bridges East and West.
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