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Open Access What to Do with Epicardial Coronary Artery Abnormalities That do not Result in Myocardial Ischemia?

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This article is Open Access under the terms of the Creative Commons CC BY-NC licence.

When epicardial arteries with minimal CAD do not limit flow are found at coronary angiography, all cardiologists agree that aggressive risk factor modification and use of appropriate drugs are warranted. Some consider plaque sealing of minor coronary lesions with balloon angioplasty to prevent future infarction. Others believe that a coronary lesion that does not cause ischemia should not have the plaque sealed but should have FFR and the non-ischemia producing stenosis should be treated with aggressive risk factor modification (DEFER study). Evidence based data e.g. DEFER, relates to populations, not the individual. Thus these data provide guidelines, which are suggestions for decision making. The weight of evidence favors angioplasty/stent for epicardial vessels that result in myocardial ischemia. Sealing of non flow limiting plaques with angioplasty must await further information derived from invasive and non invasive studies.
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Keywords: Minimal CAD; plaque sealing

Document Type: Research Article

Publication date: July 1, 2019

This article was made available online on June 18, 2019 as a Fast Track article with title: "What to Do with Coronary Artery Abnormalities That do not Result in Myocardial Ischemia?".

More about this publication?
  • Cardiovascular Innovations and Applications (CVIA) publishes focused articles and original clinical research that explore novel developments in cardiovascular disease, effective control and rehabilitation in cardiovascular disease, and promote cardiovascular innovations and applications for the betterment of public health globally. The journal publishes basic research that has clinical applicability in order to promote timely communication of the latest insights relating to coronary artery disease, heart failure, hypertension, cardiac arrhythmia, prevention of cardiovascular disease with a heavy emphasis on risk factor modification. Cardiovascular Innovations and Applications is the official journal of the Great Wall International Congress of Cardiology (GW-ICC). It aims to continue the work of the GW-ICC by providing a global scientific communication platform for cardiologists that bridges East and West.

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