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Open Access Heart Disease in Pregnancy: A Special Look at Peripartum Cardiomyopathy

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This article is Open Access under the terms of the Creative Commons CC BY-NC licence.

Peripartum cardiomyopathy (PPCM) is a disorder in which heart failure develops in the last month of pregnancy or within the first five months postpartum. The exact etiology is not known although recent studies suggest angiogenic imbalance is a key factor with soluble fms-like tyrosine kinase-1 (sFlt1) and a cleaved form of prolactin possibly playing important roles. This review discusses the epidemiology, risk factors, diagnosis, treatment and prognosis of PPCM and highlights recent advances in our understanding of this disorder.
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Keywords: Peripartum; cardiomyopathy; heart failure

Document Type: Research Article

Publication date: 01 February 2019

This article was made available online on 16 January 2019 as a Fast Track article with title: "Heart Disease in Pregnancy: A Special Look at Peripartum Cardiomyopathy".

More about this publication?
  • Cardiovascular Innovations and Applications (CVIA) publishes focused articles and original clinical research that explore novel developments in cardiovascular disease, effective control and rehabilitation in cardiovascular disease, and promote cardiovascular innovations and applications for the betterment of public health globally. The journal publishes basic research that has clinical applicability in order to promote timely communication of the latest insights relating to coronary artery disease, heart failure, hypertension, cardiac arrhythmia, prevention of cardiovascular disease with a heavy emphasis on risk factor modification. Cardiovascular Innovations and Applications is the official journal of the Great Wall International Congress of Cardiology (GW-ICC). It aims to continue the work of the GW-ICC by providing a global scientific communication platform for cardiologists that bridges East and West.

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