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Open Access Diabetes Mellitus and Stable Ischemic Heart Disease

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This article is Open Access under the terms of the Creative Commons CC BY-NC licence.

More than 30 million Americans have diabetes mellitus (DM), and heart disease is the cause of death in 68% of them. Patients with DM are at increased risk of developing stable ischemic heart disease (SIHD) by several mechanisms. While noninvasive testing for ischemia is an intuitive strategy to reduce cardiovascular events, trial data do not show a clear benefit. For the DM patient with no symptoms and no evidence of SIHD, two randomized trials found no benefit for either nuclear stress or cardiac computed tomography. While silent ischemia is associated with increased cardiovascular risk, on a population level, reducing ischemia does not appear to improve outcomes. Another important consideration in the management of SIHD in DM patients is that recent randomized trial data show no benefit from coronary revascularization for this population. In conclusion, the decision to test for ischemia may be a reasonable option in some DM patient groups; however, in many cases, revascularization for SIHD does not reduce mortality or the rate of myocardial infarction.
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Keywords: diabetes mellitus; ischemic heart disease; noninvasive testing

Document Type: Research Article

Publication date: January 1, 2019

This article was made available online on January 16, 2019 as a Fast Track article with title: "Diabetes Mellitus and Stable Ischemic Heart Disease".

More about this publication?
  • Cardiovascular Innovations and Applications (CVIA) publishes focused articles and original clinical research that explore novel developments in cardiovascular disease, effective control and rehabilitation in cardiovascular disease, and promote cardiovascular innovations and applications for the betterment of public health globally. The journal publishes basic research that has clinical applicability in order to promote timely communication of the latest insights relating to coronary artery disease, heart failure, hypertension, cardiac arrhythmia, prevention of cardiovascular disease with a heavy emphasis on risk factor modification. Cardiovascular Innovations and Applications is the official journal of the Great Wall International Congress of Cardiology (GW-ICC). It aims to continue the work of the GW-ICC by providing a global scientific communication platform for cardiologists that bridges East and West.

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