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Open Access Fractional Flow Reserve Measurement by Coronary Computed Tomography Angiography: A Review with Future Directions

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Invasive fractional flow reserve (FFR) measurement is currently the gold standard for coronary intervention. FFR measurement by coronary computed tomography angiography (FFRCT) is a novel and promising imaging technology that permits noninvasive assessment of physiologically significant coronary lesions. FFRCT is capable of combining the anatomic information provided by coronary computed tomography angiography with computational fluid dynamics to compute FFR. To date, several studies have reported the diagnostic performance of FFRCT compared with invasive FFR measurement as the reference standard. Further studies are now being implemented to determine the clinical feasibility and economic implications of FFRCT techniques. This article provides an overview and discusses the available evidence as well as potential future directions of FFRCT.
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Keywords: Fractional flow reserve; computational fluid dynamics; coronary computed tomography angiography; fractional flow reserve measurement by coronary computed tomography angiography

Document Type: Research Article

Publication date: December 1, 2016

This article was made available online on February 9, 2017 as a Fast Track article with title: "Fractional Flow Reserve Measurement by Coronary Computed Tomography Angiography: A Review with Future Directions".

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  • Cardiovascular Innovations and Applications (CVIA) publishes focused articles and original clinical research that explore novel developments in cardiovascular disease, effective control and rehabilitation in cardiovascular disease, and promote cardiovascular innovations and applications for the betterment of public health globally. The journal publishes basic research that has clinical applicability in order to promote timely communication of the latest insights relating to coronary artery disease, heart failure, hypertension, cardiac arrhythmia, prevention of cardiovascular disease with a heavy emphasis on risk factor modification. Cardiovascular Innovations and Applications is the official journal of the Great Wall International Congress of Cardiology (GW-ICC). It aims to continue the work of the GW-ICC by providing a global scientific communication platform for cardiologists that bridges East and West.

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