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Home / Cryoletters, Volume 44, Number 4

Open Access Cryobiology and fertility preservation: A perspective on past, current and future studies

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Cryopreservation has been used over many decades for the maintenance of viable biological specimens. Its expansion into the area of fertility preservation has been a natural outcome of the increased risks to human fertility from diseases, such as cancer and its treatment protocols, including radiation and chemo-therapy, and thegeneral lifestyle trend to later marriages. The use of assisted reproductive techniques (ART) in preserving fertility have benefitted significantly from new scientific approaches, such as cryostorage, in which live cells and tissues are stored at low temperatures and revived when necessary. This review focuses on "cryopreservation science monitoring in reproductive biomedicine" to evaluate knowledge, trends, driving forces, impetus, and emerging technologies in order to draw a future roadmap for this field. Our analysis of the field of cryobiology emphasises the significance of strategic planning of cryobiology research to support more its extensive use in therapeutics in the future. The Royan Institute (Tehran, Iran) recognises this need and has developed a plan to engage in multidisciplinary research on the application of cryobiology, including in disease mitigation. We hope that this study can help improve the quality and of public discourse and expert awareness of the role for cryopreservation in fertility within ART.

Keywords: CRYOBIOLOGY; CRYOPRESERVATION; FERTILITY PRESERVATION; REPRODUCTION

Document Type: Research Article

Affiliations: 1: Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran 2: Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran,Iran 3: Human and Animal Cell Bank, Iranian Biological Resource Center(IBRC), ACECR, Tehran, Iran.; Futures Studies Office, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran 4: Department of Industrial Management, Faculty of Management, Imam Sadiq University, Tehran, Iran 5: Future Studies Office, Supreme National Defense University, Babaei Highway, Tehran, Iran 6: Department of Regenerative Biomedicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.; Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran 7: Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.; Department of Anatomy, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran 8: Infertility Center of St. Louis, 224 South Woods Mill Road, Suite 730, Saint Louis, MO, 63017, USA 9: Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.; Futures Studies Office, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran

Publication date: July 1, 2023

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  • CryoLetters is a bimonthly international journal for low temperature sciences, including cryobiology, cryopreservation or vitrification of cells and tissues, chemical and physical aspects of freezing and drying, and studies involving ecology of cold environments, and cold adaptation

    The journal publishes original research reports, authoritative reviews, technical developments and commissioned book reviews of studies of the effects produced by low temperatures on a wide variety of scientific and technical processes, or those involving low temperature techniques in the investigation of physical, chemical, biological and ecological problems.

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