Skip to main content
padlock icon - secure page this page is secure

Decellularization and Recellularization Technologies in Tissue Engineering


The full text article is temporarily unavailable.

We apologise for the inconvenience. Please try again later.

Decellularization is the process by which cells are discharged from tissues/organs, but all of the essential cues for cell preservation and homeostasis are retained in a three-dimensional structure of the organ and its extracellular matrix components. During tissue decellularization, maintenance of the native ultrastructure and composition of the extracellular matrix (ECM) is extremely acceptable. For recellularization, the scaffold/matrix is seeded with cells, the final goal being to form a practical organ. In this review, we focus on the biological properties of the ECM that remains when a variety of decellularization methods are used, comparing recellularization technologies, including bioreactor expansion for perfusion-based bioartificial organs, and we discuss cell sources. In the future, decellularization‐recellularization procedures may solve the problem of organ assembly on demand.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Biomaterial; Decellularization; Extracellular matrix (ECM); Organ bioengineering and regeneration; Recellularization

Document Type: Research Article

Affiliations: Graduate Institute of Immunology, China Medical University, Taichung, Taiwan

Publication date: April 9, 2014

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more