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Cyanobacterial toxins and liver disease

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Blue-green algae, also known as cyanobacteria, produce a variety of toxins, some of which have been implicated in the pathogenesis of severe and potentially life-threatening diseases in humans. As the growth of cyanobacteria within freshwater lakes increases worldwide, it is important to review our present understanding of their toxicity and potential carcinogenicity to gain insight into how these organisms impact human health. This review addresses each of these topics, with special emphasis given to cyanobacterial hepatotoxins within freshwater environments.

Les algues bleu-vert, aussi connues sous le nom de cyanobactéries, produisent divers types de toxines. Certaines de ces toxines ont été impliquées dans la pathogenèse de maladies graves parfois mortelles chez les humains. Compte tenu de l’augmentation du nombre des cyanobactéries dans les lacs à l’eau douce à travers le monde, il est important de revoir notre compréhension de l’hépatotoxicité et de la carcinogénicité qui lui est associée afin de mieux comprendre le lien entre ces organismes et la maladie du foie. La présente synthèse aborde chacun de ces thèmes et porte une attention particulière aux hépatotoxines cyanobactériennes dans les milieux d’eau douce.
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Document Type: Research Article

Publication date: October 1, 2009

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