Skip to main content
padlock icon - secure page this page is secure

The association between arterial properties and blood pressure in children

Buy Article:

$36.38 + tax (Refund Policy)

Elevated blood pressure (BP) in adults is associated with increased arterial stiffness and thickness; however, its effect on arterial health in a pediatric population is less understood. The purpose of this study was to identify the relationship between childhood BP and arterial markers of arteriosclerotic progression. The study consisted of 106 children across a wide range of BP values divided into 2 BP groups: high BP (HBP; ≥95th percentile; n = 21) and normal BP (NBP; <90th percentile; n = 85) based on consistent automated BP measures taken at 2 time points. The laboratory examination involved systemic pulse wave velocity (PWV), common carotid artery (CCA) intima media thickness (IMT) and distensibility, as well as body mass index (BMI) and pubertal maturation. BMI and heart rate, as well as PWV (HBP: n = 15 and NBP: n = 56), were higher in the HBP group (p < 0.001) with no difference between groups for both CCA distensibility and IMT (HBP: n = 21 and NBP: n = 83). Multivariate linear regression revealed that BP group (p = 0.003) was an independent predictor of PWV after controlling for age, sex, BMI, heart rate, and maturation. Our findings demonstrate a higher systemic PWV with no difference in CCA IMT or distensibility in children with elevated BP. Hence, markers of cardiovascular disease risk are augmented in healthy children with elevated BP.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Keywords: artère carotide commune; common carotid artery; distensibility; distensibilité; intima-media thickness; maturation; pulse wave velocity; vélocité de l’onde pulsatile; épaisseur de l’intima-média

Document Type: Research Article

Affiliations: 1: Experimental Medicine, University of British Columbia, Vancouver, BC V5Z 1M9, Canada. 2: Department of Health Sciences, Faculty of Applied Health Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada. 3: School of Kinesiology, University of Western Ontario, London, ON N6A 5B9, Canada. 4: Department of Kinesiology, Waterloo University, Waterloo, ON N2L 3G1, Canada. 5: Departments of Psychiatry and Behavioural Neuroscience, Family Medicine, Kinesiology, and CanChild, Centre for Childhood Disability Research, McMaster University, Hamilton, ON L8P 0A1, Canada.

Publication date: January 1, 2015

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more