@article {Riou:2009:1715-5312:99,
title = "Predictors of cardiovascular fitness in sedentary men",
journal = "Applied Physiology, Nutrition, and Metabolism",
parent_itemid = "infobike://cndscipub/apnm",
publishercode ="cndscipub",
year = "2009",
volume = "34",
number = "2",
publication date ="2009-04-01T00:00:00",
pages = "99-106",
itemtype = "ARTICLE",
issn = "1715-5312",
eissn = "1715-5320",
url = "https://www.ingentaconnect.com/content/cndscipub/apnm/2009/00000034/00000002/art00002",
author = "Riou, Marie-{\‘E}ve and Pigeon, {\’E}tienne and St-Onge, Jos{\’e}e and Tremblay, Angelo and Marette, Andr{\’e} and Weisnagel, S. J. and Joanisse, Denis R.",
abstract = "The relative contribution of anthropometric and skeletal muscle characteristics to cardiorespiratory fitness was studied in sedentary men. Cardiorespiratory fitness (maximal oxygen consumption) was assessed using an incremental bicycle ergometer protocol in 37 men aged 34-53years.
Vastus lateralis muscle biopsy samples were used to assess fiber type composition (I, IIA, IIX) and areas, capillary density, and activities of glycolytic and oxidative energy metabolic pathway enzymes. Correlations (all p< 0.05) were observed between maximal oxygen consumption
(L\textperiodcenteredmin-1) and body mass (r = 0.53), body mass index (r = 0.39), waist circumference (r = 0.34), fat free mass (FFM; r = 0.68), fat mass (r = 0.33), the enzyme activity of cytochrome c oxidase (COX; r = 0.39), muscle type IIA
(r = 0.40) and IIX (r = 0.50) fiber area, and the number of capillaries per type IIA (r = 0.39) and IIX (r = 0.37) fiber. When adjusted for FFM in partial correlations, all correlations were lost, with the exception of COX (r = 0.48). Stepwise multiple regression
revealed that maximal oxygen consumption was independently predicted by FFM, COX activity, mean capillary number per fiber, waist circumference, and, to a lesser extent, muscle capillary supply. In the absence of regular physical activity, cardiorespiratory fitness is strongly predicted by
the potential for aerobic metabolism of skeletal muscle and negatively correlated with abdominal fat deposition.La contribution relative de variables anthropom{\’e}triques et de caract{\’e}ristiques du muscle squelettique {\‘a} la capacit{\’e} maximale {\‘a} leffort
(consommation maximale de loxyg{\‘e}ne) {\‘a} {\’e}t{\’e} {\’e}valu{\’e}e chez des hommes s{\’e}dentaires. La consommation maximale de loxyg{\‘e}ne a {\’e}t{\’e} mesur{\’e} {\‘a} laide dun test progressif sur v{\’e}lo ergocycle
chez 37 hommes {\^a}g{\’e}s de 34 {\‘a} 53 ans. Des biopsies du vastus lateralis ont servi pour d{\’e}terminer la composition en fibres musculaires (I, IIA, IIX) et leurs aires, la densit{\’e} des capillaires, et des activit{\’e}s denzymes de la glycolyse et du m{\’e}tabolisme
{\’e}nerg{\’e}tique oxydatif. Des corr{\’e}lations (toutes p-1) et la masse corporelle (r = 0,53), lindice de masse corporelle
(r = 0,39), la circonf{\’e}rence de taille (r = 0,34), la masse maigre (r = 0,68), la masse grasse (r= 0,33), lactivit{\’e} enzymatique de la cytochromec oxydase (COX; r = 0,39), la surface des fibres de type IIA (r
= 0,40) et IIX (r = 0,50), et le nombre de capillaires par fibre de type IIA (r = 0,39) et IIX (r = 0,37). Ajust{\’e}es pour la masse maigre dans des corr{\’e}lations partielles, toutes ces corr{\’e}lations disparurent sauf celle avec la COX (r = 0,48).
Analys{\’e} par r{\’e}gression multiple, la consommation maximale de loxyg{\‘e}ne {\’e}tait ind{\’e}pendamment pr{\’e}dit par la masse maigre, lactivit{\’e} de la COX, la circonf{\’e}rence de taille, et {\‘a} un moindre niveau par la capillarit{\’e}
des fibres musculaires. Chez lhomme s{\’e}dentaire, la consommation maximale de loxyg{\‘e}ne est fortement pr{\’e}dite par le potentiel a{\’e}robique du muscle squelettique et n{\’e}gativement corr{\’e}l{\’e}e avec lob{\’e}sit{\’e} abdominale.",
}