Use of Pelvic Flexure Biopsy Scores to Predict Short‐Term Survival after Large Colon Volvulus
To (1) determine if histologic scores of pelvic flexure biopsies can predict short‐term survival in horses with large colon volvulus (LCV) and (2) identify clinical variables predictive of short‐term survival.
Horses (n = 28) with LCV (≥360°).
Medical records (January 2000–February 2008) of 28 horses were reviewed and clinical data recorded. Pelvic flexure biopsies were reviewed by 2 board‐certified veterinary pathologists, unaware of clinical history and outcome, using 2 scoring systems. Exact logistic regression analysis was used to determine the relationship between histopathology scores (tissue viability), clinical data, and short‐term survival (hospital discharge).
Twenty‐four horses (86%) survived to hospital discharge. Using a similar cutoff, neither scoring system was capable of predicting short‐term survival. One scoring system failed to correctly predict clinical outcome in 5/25 horses (20%) and the other failed in 6/28 horses (22.4%). Heart rate (at admission and 24 hours after surgery) and packed cell volume 24 hours after surgery were significantly associated with short‐term survival.
Histopathologic evaluation of pelvic flexure biopsies did not accurately predict short‐term survival in a significant proportion of horses with LCV in this study.
No Supplementary Data
No Article Media
Document Type: Research Article
Publication date: July 1, 2012