Canine pyoderma gangrenosum: a case series of two dogs
Pyoderma gangrenosum (PG) is a rare disease, which, to the best of the authors' knowledge, has been the subject of only one case report in the peer‐reviewed veterinary literature.
To describe the history, clinical signs, diagnostic findings and treatment outcome in two cases of canine PG.
Two client‐owned dogs presented to a private veterinary referral practice between 2008 and 2010 who received a diagnosis of PG by specialist veterinary dermatologists.
Medical records were analysed to retrieve relevant information.
Both dogs were treated with prednisolone; this was combined with ciclosporin in case 1 and azathioprine in case 2. Case 2 had a more complete response of lesions to treatment and a longer survival time after diagnosis (763 days) than case 1 (81 days).
Pyoderma gangrenosum is a rare disease distinguished by rapid progression of painful, necrolytic, cutaneous ulcers with irregular, violaceous undermined borders. Azathioprine with glucocorticoids may lead to a better outcome than ciclosporin and glucocorticoids (currently the first‐line treatment in humans and the only reported treatment in dogs).
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Document Type: Research Article
Publication date: October 1, 2013