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Zinc-responsive dermatosis in dogs: 41 cases and literature review

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Forty-one cases of zinc-responsive dermatosis in the dog are described. The Siberian husky was the predominant breed affected. Periocular crusts were the most common clinical sign and parakeratosis was noted in the skin biopsy specimens of all dogs. Treatment with oral zinc ameliorated the clinical signs in most dogs, but cases necessitating other treatments such as parenteral zinc or retinoids are reported. The authors recommend a starting dose of 2–3 mg kg−1 elemental zinc per day in the treatment of this disorder.
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Keywords: Siberian husky; crusting skin; dogs; parakeratosis; skin; zinc

Document Type: Research Article

Affiliations: 1: Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA; 2: Departement Pathologie Generale Infectieuse et Parasitaire, Ecole Nationale Vétérinaire de Nantes BP 44307, Nantes Cedex 03, France; 3: Department of Clinical Sciences, School of Veterinary Medicine, Colorado State University, Fort Collins, Colorado 80523, USA; 4: Department of Biology, Colorado State University, Fort Collins, Colorado 80523, USA; 5: Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, California 95616, USA; 6: Veterinary Teaching Hospital, School of Veterinary Medicine, Colorado State University, Fort Collins, Colorado 80523, USA; 7: Department of Statistics, Colorado State University, Fort Collins, Colorado 80523, USA; 8: Department of Pathology, Colorado State University, Fort Collins, Colorado 80523, USA; , 9: Koret Veterinary Teaching Hospital, School of Veterinary Medicine, The Hebrew University of Jerusalem, PO Box 12 Rehovot 70600, Israel; 10: Animal Dermatology and Allergy, Loomis, California 95650, USA; 11: Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, California 95616, USA

Publication date: April 1, 2001

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